While the search for a "Euro Truck Simulator PS2 ISO" is understandable, the unfortunate truth is that the game simply does not exist for that console. The files you find online are likely dangerous fakes or mislabeled older trucking games.
You might also encounter references to Truck Driver . However, this game was released for PS4, Xbox One, and Nintendo Switch. It is often confused with the PS2 era due to its "legacy" graphical style, but it is a PS2 game and will not run on a PS2 or standard PS2 emulator. Euro Truck Simulator Ps2 Iso