Perhaps the most profound development is how trans experience is leaking out of the "community" and into the broader culture, changing how all queer people—and even cishet people—live.
Early gay rights relied heavily on the idea that sexual orientation is innate and immutable. But trans experience challenges simple biological essentialism. If gender identity can be distinct from biological sex, then perhaps sexuality is also more fluid. Many younger queer people now see sexuality and gender as intersecting spectrums, not fixed categories. This has led to the rise of terms like "pansexual" and "queer" as umbrella identifiers, moving beyond the gay/straight binary.
Transgender women of color experience disproportionately high rates of violence.